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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROM1 All Species: 7.88
Human Site: Y696 Identified Species: 19.26
UniProt: O43490 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43490 NP_006008.1 865 97202 Y696 E Q S L S T L Y Q S V K I L Q
Chimpanzee Pan troglodytes XP_517115 865 97216 Y696 E Q S L S T L Y Q S V K I L Q
Rhesus Macaque Macaca mulatta NP_001070888 841 94490 A674 R N S L K R D A Q T I K T I H
Dog Lupus familis XP_850831 831 93500 G665 K A N N L P Q G S L K Q S L K
Cat Felis silvestris
Mouse Mus musculus O54990 867 97095 R698 Q Q S L N T L R Q S V W T L Q
Rat Rattus norvegicus Q8CJ52 834 92822 L668 E A R E L R S L Y Q E K V V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515242 740 82713 L574 T L N Q S I R L L Q K T A T E
Chicken Gallus gallus XP_001232165 871 96765 N701 E Q A M S T L N Q S I R L L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9W735 826 91929 S659 D A Q A D Q L S K G T L Q T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798860 858 93747 S690 A T A L N D I S A D L Q T L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.1 63.5 N.A. 60.6 26.5 N.A. 44.3 52.8 N.A. 41.7 N.A. N.A. N.A. N.A. 26.9
Protein Similarity: 100 99.4 94.9 80.1 N.A. 78.7 48.3 N.A. 62.3 73.7 N.A. 63.3 N.A. N.A. N.A. N.A. 45.7
P-Site Identity: 100 100 26.6 6.6 N.A. 66.6 13.3 N.A. 6.6 53.3 N.A. 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 46.6 33.3 N.A. 80 26.6 N.A. 20 93.3 N.A. 20 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 30 20 10 0 0 0 10 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 10 10 0 0 10 0 0 0 0 0 % D
% Glu: 40 0 0 10 0 0 0 0 0 0 10 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 10 10 0 0 0 20 0 20 10 0 % I
% Lys: 10 0 0 0 10 0 0 0 10 0 20 40 0 0 20 % K
% Leu: 0 10 0 50 20 0 50 20 10 10 10 10 10 60 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 20 10 20 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 10 40 10 10 0 10 10 0 50 20 0 20 10 0 40 % Q
% Arg: 10 0 10 0 0 20 10 10 0 0 0 10 0 0 0 % R
% Ser: 0 0 40 0 40 0 10 20 10 40 0 0 10 0 10 % S
% Thr: 10 10 0 0 0 40 0 0 0 10 10 10 30 20 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 30 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 20 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _